Treatable Diseases and Future Uses of Umbilical Cord Blood Stem Cells Umbilical Cord Blood -

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Treatable Diseases and Future Uses of Umbilical Cord Blood Stem Cells



Today, cord blood stems cells are used in the treatment of over 40 life-threatening diseases, including a wide range of cancers, genetic diseases, immune system deficiencies, and blood disorders (see list below). To learn more about potential future uses for cord blood stem cells click here. Cancers
Acute lymphoblastic leukemia (ALL) Acute myelogenous leukemia (AML) Burkitt's lymphoma Chronic myelogenous leukemia (CML) Juvenile chronic myelogenous leukemia (JCML) Juvenile myelomonocytic leukemia (JMML) Liposarcoma Myelodysplastic syndrome (MDS) Chronic myelomonocytic leukemia (CMML) Neuroblastoma Non-Hodgkin's lymphoma Hodgkin's lymphoma Bone Marrow Failure Systems Severe aplastic anemia
Diamond-Blackfan anemia Dyskeratosis congenita Fanconi anemia Amegakaryocytic thrombocytopenia Kostmann's syndrome Hemoglobinpathies/Blood Disorders Sickle-cell anemia
ß-Thalassemia (Cooley's anemia) Inborn Errors of Metabolism Adrenoleukodystrophy
Batten disease (inherited neuronal ceroid lipofuscinosis) Gunther disease Hunter syndrome Hurler syndrome Krabbe disease (globoid cell leukodystrophy) Lesch-Nyhan disease Maroteaux-Lamy syndrome Immunodeficiencies Omenn's syndrome
Severe combined immune deficiency (SCID and SCID-ADA) Reticular dysplasia Thymic dysplasia Wiskott-Aldrich syndrome X-linked lymphoproliferative disease Leukocyte adhesion deficiency Other Diseases Langerhan's cell histiocytosis
Evans syndrome Familial hemaphagocytic lymphohistiocytosis EBV-assoc. hemophagocytic lymphohistiocytosis Osteopetrosis Although the potential use of umbilical cord blood is expanding rapidly, the odds that family member without a defined risk will need to use their child's umbilical cord blood are low. There is no guarantee that the umbilical cord blood will be a match for a family member or will provide a cure. Autologous cord blood stem cells will not guarantee suitable treatment for all inherited genetic diseases. As will any transplant therapy, therapeutic success depends upon many factors beyond the stem cells themselves including patient condition, type of disease, recipient-donor relationship and matching, and other



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